Combination of bolus and continuous infusion of factor VIII in a patient with severe hemophilia A undergoing on-pump coronary artery bypass graft surgery

Stanislaw Vander Zwaag; Stefan Brose; Jens Fassl

doi:10.1002/ccr3.9468

Combination of bolus and continuous infusion of factor VIII in a patient with severe hemophilia A undergoing on-pump coronary artery bypass graft surgery

Clin Case Rep. 2024 Nov 1;12(11):e9468. doi: 10.1002/ccr3.9468. eCollection 2024 Nov.

Authors

Stanislaw Vander Zwaag¹, Stefan Brose², Jens Fassl¹

Affiliations

¹ Department of Cardiac Anesthesiology, Heart Center Dresden University Hospital Dresden Germany.
² Department of Cardiac Surgery, Heart Center Dresden University Hospital Dresden Germany.

Abstract

Patients with hemophilia A can safely undergo cardiac surgery. Combining continuous infusion and boluses of factor VIII is both safe and cost-effective. Interdisciplinary approach and meticulous planning are crucial in the prevention of bleeding complications.

Keywords: cardiac anesthesia; cardiac surgery; coronary artery disease; hemophilia A.