Rhabdomyolysis is a relatively rare condition caused by the damage and release of myocyte contents. It occurs most commonly secondary to strenuous exercise. Rhabdomyolysis carries the risk of life-threatening negative sequelae such as acute kidney injury or death. This case report describes a middle-aged male patient who has presented with rhabdomyolysis five times over the past nine years, each following a viral illness. No inborn errors of metabolism, neuromuscular junction conditions, or myopathies were found to explain the patient's recurrent rhabdomyolysis except for two variants of unknown significance in the SYNE2 gene that has been linked with Emery-Dreifuss muscular dystrophy.
Keywords: covid-19; emery-dreifuss muscular dystrophy; idiopathic rhabdomyolysis; non-traumatic rhabdomyolysis; post-influenza; viral-induced rhabdomyolysis.
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