Extradigital Symplastic Glomus Tumor and Review of the Literature

Am J Dermatopathol. 2025 Jan 1;47(1):42-45. doi: 10.1097/DAD.0000000000002883. Epub 2024 Nov 5.

Abstract

Symplastic glomus tumors are a rare subtype of glomus tumor defined by nuclear atypia without additional markers of malignancy such as large size, deep location, or atypical/prevalent mitotic figures. Glomus tumors, including the symplastic subtype, most commonly present in the subungual area with rarer extradigital presentation. To our knowledge, there have been less than 25 cases of symplastic glomus tumors described in the literature. Herein, we present a case of extradigital symplastic glomus tumor with review of the literature.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Female
  • Fingers / pathology
  • Glomus Tumor* / chemistry
  • Glomus Tumor* / pathology
  • Glomus Tumor* / surgery
  • Humans
  • Immunohistochemistry
  • Male
  • Middle Aged
  • Skin Neoplasms / pathology
  • Skin Neoplasms / surgery