Hepatic Perfusion for Diffuse Metastatic Cancer to the Liver: Open and Percutaneous Techniques

Hematol Oncol Clin North Am. 2025 Feb;39(1):177-190. doi: 10.1016/j.hoc.2024.08.007.

Abstract

The management of patients with diffuse liver metastases remains a significant clinical challenge. In many cancer patients, metastatic disease may be isolated to the liver or the liver may be the dominant site of progressive metastatic cancer. In this setting, progression of disease in the liver generally is the most significant cause of morbidity and mortality.

Keywords: Diffuse liver; Hepatic perfusion; IHP; Liver metastases; Metachronous disease; Metastatic cancer; PHP.

Publication types

  • Review

MeSH terms

  • Chemotherapy, Cancer, Regional Perfusion / methods
  • Humans
  • Liver / pathology
  • Liver Neoplasms* / secondary
  • Liver Neoplasms* / therapy