Multiple skin abscesses due to Nocardia neocaledoniensis: a case report and literature review

BMC Infect Dis. 2024 Nov 7;24(1):1259. doi: 10.1186/s12879-024-10177-7.

Abstract

N. neocaledoniensis is a very rare infectious pathogen that causes human disease, particularly in immunocompromised individuals. In this case report, we describe the successful diagnosis of N. neocaledoniensis in a patient confirmed by mNGS and the treatment of multiple skin abscesses due to N. neocaledoniensis infection. mNGS is an important diagnostic method complementary to routine bacterial culture and identification methods, especially for rare, novel, co-infected pathogens, and pathogens that are difficult to culture. This report may provide a reference for the clinical treatment and diagnosis of N. neocaledoniensis infection in humans.

Keywords: N. Neocaledoniensis; Case report; Multiple skin abscesses; mNGS.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Abscess* / drug therapy
  • Abscess* / microbiology
  • Anti-Bacterial Agents / therapeutic use
  • Humans
  • Male
  • Middle Aged
  • Nocardia Infections* / diagnosis
  • Nocardia Infections* / drug therapy
  • Nocardia Infections* / microbiology
  • Nocardia* / genetics
  • Nocardia* / isolation & purification
  • Skin Diseases, Bacterial / drug therapy
  • Skin Diseases, Bacterial / microbiology
  • Skin Diseases, Bacterial / pathology

Substances

  • Anti-Bacterial Agents