Laparoscopic versus open lumbar sympathectomy in critical limb threatening ischemia patients in Egypt

BMC Surg. 2024 Nov 7;24(1):350. doi: 10.1186/s12893-024-02618-6.

Abstract

Purpose: The treatment of critical limb-threatening ischemia (CLTI) is revascularization. Lumbar sympathectomy (LS) could be attempted when this is not amenable. Using laparoscopic techniques to perform LS adds the advantages of minimally invasive surgery.

Methods: Twenty-four patients, presenting with non-reconstructable CLTI and rest pain, were randomly divided into group I (14 patients) who underwent retroperitoneoscopic lumbar sympathectomy (RPLS) and group II (10 patients) who had conventional open lumber sympathectomy (COLS).

Results: RPLS patients had shorter hospital stays, fewer intraoperative complications, and less postoperative pain. However, the mean operative time was significantly longer (86.4 ± 9.1 min, p-value: 0.02) in the RPLS group but decreased with each subsequent case after that. The differences in post-operative capillary refill time, ABI, TBI, and TcPO2 were not statistically significant between both groups (p-values: 0.97, 0.13, 0.32, 0.10, respectively). However, the difference in the quality-of-life score was statistically significant; the mean (± SD) SF-36 score increased from 48 ± 6.8 to 81 ± 4.4 (p-value < 0.001) in RPLS group compared to 52 ± 8.8 to 59 ± 1.2 (p-value: 0.52) in COLS group.

Conclusion: RPLS is feasible, safe, and has the advantages of minimally invasive surgery: minimal blood loss, less intraoperative complications, shorter hospital stay, and less postoperative pain. However, the operative time in RPLS cases is longer than in the COLS; training on the procedure is recommended to improve the learning curve.

Keywords: Chronic limb-threatening ischemia; Critical limb ischemia; Laparoscopic assisted surgery; Laparoscopic surgery; Laparoscopic sympathectomy; Laparoscopy; Lumbar sympathectomy; Peripheral arterial disease; Peripheral artery disease; Peritoneoscopy; Sympathectomy; Sympathetic denervation.

Publication types

  • Randomized Controlled Trial
  • Comparative Study

MeSH terms

  • Adult
  • Egypt
  • Female
  • Humans
  • Ischemia* / surgery
  • Laparoscopy* / methods
  • Length of Stay / statistics & numerical data
  • Lumbosacral Plexus / surgery
  • Male
  • Middle Aged
  • Operative Time
  • Sympathectomy* / methods
  • Treatment Outcome