From agammaglobulinemia to neutropenia: 'The TCF-3 has different clinical presentations'

Scand J Immunol. 2024 Dec;100(6):e13423. doi: 10.1111/sji.13423. Epub 2024 Nov 10.

Authors

Hulya Kose¹, Akcahan Akalin², Sara Sebnem Kilic³

Affiliations

¹ Department of Pediatric Immunology and Allergy, Diyarbakir Children's Hospital, Diyarbakir, Turkey.
² Department of Pediatric Genetics, Diyarbakir Children's Hospital, Diyarbakir, Turkey.
³ Department of Pediatric Immunology and Rheumatology, Bursa Uludag University Faculty of Medicine, Bursa, Turkey.

PMID: 39523462
DOI: 10.1111/sji.13423

Abstract

The clinical picture of the TCF3 deficiency may manifest differently from neutropenia to antibody production defects.

© 2024 The Scandinavian Foundation for Immunology.

Publication types

Letter

MeSH terms

Agammaglobulinemia* / diagnosis
Agammaglobulinemia* / immunology
Basic Helix-Loop-Helix Leucine Zipper Transcription Factors / genetics
Basic Helix-Loop-Helix Transcription Factors
Humans
Mutation
Neutropenia* / diagnosis
Neutropenia* / immunology

Substances

TCF3 protein, human
Basic Helix-Loop-Helix Leucine Zipper Transcription Factors
Basic Helix-Loop-Helix Transcription Factors