A one health roadmap towards understanding and mitigating emerging Fungal Antimicrobial Resistance: fAMR

Matthew C Fisher; Fiona Burnett; Clare Chandler; Neil A R Gow; Sarah Gurr; Alwyn Hart; Alison Holmes; Robin C May; Janet Quinn; Tarek Soliman; Nicholas J Talbot; Helen M West; Jon S West; P Lewis White; Michael Bromley; Darius Armstrong-James

doi:10.1038/s44259-024-00055-2

A one health roadmap towards understanding and mitigating emerging Fungal Antimicrobial Resistance: fAMR

NPJ Antimicrob Resist. 2024;2(1):36. doi: 10.1038/s44259-024-00055-2. Epub 2024 Nov 7.

Authors

Matthew C Fisher¹, Fiona Burnett², Clare Chandler³, Neil A R Gow⁴, Sarah Gurr⁵, Alwyn Hart⁶, Alison Holmes⁷, Robin C May⁸, Janet Quinn⁹, Tarek Soliman², Nicholas J Talbot¹⁰, Helen M West¹¹, Jon S West¹², P Lewis White¹³, Michael Bromley¹⁴, Darius Armstrong-James¹⁵

Affiliations

¹ MRC Centre for Global Infectious Disease Outbreak Analysis, Imperial, London, UK.
² Scotland's Rural College (SRUC), West Mains Road, Edinburgh, UK.
³ Department of Global Health & Development, London School of Hygiene & Tropical Medicine, 15-17 Tavistock Place, London, UK.
⁴ Medical Research Council Centre for Medical Mycology, University of Exeter, Geoffrey Pope Building, Stocker Road, Exeter, UK.
⁵ Biosciences, University of Exeter, Exeter, UK.
⁶ Chief Scientist's Group, Environment Agency, Bristol, UK.
⁷ Pharmacology and Therapeutics, University of Liverpool, Liverpool, UK.
⁸ School of Biosciences, The University of Birmingham, Birmingham, UK.
⁹ Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK.
¹⁰ The Sainsbury Laboratory, University of East Anglia, Norwich Research Park, Colney Lane Norwich, UK.
¹¹ School of Biosciences, University of Nottingham, Sutton Bonington Campus, Loughborough, UK.
¹² Protecting Crops and the Environment, Rothamsted Research, Harpenden, UK.
¹³ Public Health Wales Mycology Reference Laboratory, University Hospital of Wales, Cardiff, UK.
¹⁴ Manchester Fungal Infection Group, University of Manchester, Manchester, UK.
¹⁵ Department of Infectious Diseases, Imperial, London, UK.

Abstract

The emergence of fungal antimicrobial resistance-fAMR-is having a growing impact on human and animal health, and food security. This roadmap charts inter-related actions that will enhance our ability to mitigate the risk of fAMR. As humanity's reliance on antifungal chemicals escalates, our understanding of their one-health consequences needs to scale accordingly if we are to protect our ability to manage the global spectrum of fungal disease sustainably.

Keywords: Antimicrobial resistance; Fungal infection.

Publication types

Review