Editorial: Novel approaches to targeting the vasculature and metabolome to prevent brain aging and related diseases

Jennifer Ihuoma; Sharon Negri; Amanda Morato Do Canto; Anika M S Hartz; Aditi Deshpande; Stefano Tarantini

doi:10.3389/fncel.2024.1505939

Editorial: Novel approaches to targeting the vasculature and metabolome to prevent brain aging and related diseases

Front Cell Neurosci. 2024 Oct 25:18:1505939. doi: 10.3389/fncel.2024.1505939. eCollection 2024.

Authors

Jennifer Ihuoma^{1

2}, Sharon Negri^{1

2}, Amanda Morato Do Canto³, Anika M S Hartz^{4

5}, Aditi Deshpande⁶, Stefano Tarantini^{1

2

7}

Affiliations

¹ Center for Geroscience and Healthy Brain Aging, Department of Biochemistry and Molecular Biology, University of Oklahoma Health Sciences Center, Oklahoma City, OK, United States.
² Peggy and Charles Stephenson Cancer Center, University of Oklahoma Health Sciences Center, Oklahoma City, OK, United States.
³ Faculty of Medical Sciences, State University of Campinas, Campinas, Brazil.
⁴ Sanders-Brown Center on Aging, College of Medicine, University of Kentucky, Lexington, KY, United States.
⁵ Department of Pharmacology and Nutritional Sciences, College of Medicine, University of Kentucky, Lexington, KY, United States.
⁶ BioAge Labs, Richmond, CA, United States.
⁷ Hudson College of Public Health, University of Oklahoma Health Sciences Center, Oklahoma City, OK, United States.

No abstract available

Keywords: aging; blood brain barrier; brain homeostasis; cognitive decline; neurodegenerative disease; neurometabolic alterations; neurovascular uncoupling; neurovascular unit.

Publication types

Editorial

Grants and funding

The author(s) declare financial support was received for the research, authorship, and/or publication of this article. This work was supported by grants from the National Institute on Aging (NIA R03AG070479, NIA K01AG073614, NIA R21AG080775), the American Heart Association AHA CDA941290, AHA 24TPA1299954, the NIA-supported Geroscience Training Program in Oklahoma (T32AG052363), the NIA-supported Oklahoma Nathan Shock Center, and the NIGMS supported Center of Biomedical Research Excellence (CoBRE) (1P20GM125528-01A1).