Perioperative Acute Kidney Injury: Diagnosis, Prediction, Prevention, and Treatment

Nicholas J Douville; Michael Mathis; Sachin Kheterpal; Michael Heung; Jennifer Schaub; Abhijit Naik; Matthias Kretzler

doi:10.1097/ALN.0000000000005215

Perioperative Acute Kidney Injury: Diagnosis, Prediction, Prevention, and Treatment

Anesthesiology. 2025 Jan 1;142(1):180-201. doi: 10.1097/ALN.0000000000005215.

Authors

Nicholas J Douville¹, Michael Mathis², Sachin Kheterpal³, Michael Heung⁴, Jennifer Schaub⁴, Abhijit Naik⁴, Matthias Kretzler⁵

Affiliations

¹ Department of Anesthesiology, Michigan Medicine, Ann Arbor, Michigan; Institute of Healthcare Policy & Innovation, University of Michigan, Ann Arbor, Michigan; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, Michigan.
² Department of Anesthesiology, Michigan Medicine, Ann Arbor, Michigan; Institute of Healthcare Policy & Innovation, University of Michigan, Ann Arbor, Michigan; Department of Computational Medicine and Bioinformatics, Ann Arbor, Michigan.
³ Department of Anesthesiology, Michigan Medicine, Ann Arbor, Michigan.
⁴ Division of Nephrology, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan.
⁵ Department of Computational Medicine and Bioinformatics, Ann Arbor, Michigan; Division of Nephrology, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan.

Abstract

In this review, the authors define acute kidney injury in the perioperative setting, describe the epidemiologic burden, discuss procedure-specific risk factors, detail principles of management, and highlight areas of ongoing controversy and research.

Grants and funding

K08 DK131346/DK/NIDDK NIH HHS/United States