Molecular Surveillance of Multidrug-Resistant Bacteria among Refugees from Afghanistan in 2 US Military Hospitals during Operation Allies Refuge, 2021

Emerg Infect Dis. 2024 Oct;30(14):47-52. doi: 10.3201/eid3014.240152.

Abstract

In 2021, two US military hospitals, Landstuhl Regional Medical Center in Landstuhl, Germany, and Walter Reed National Military Medical Center (WRNMMC) in Bethesda, Maryland, USA, observed a high prevalence of multidrug-resistant bacteria among refugees evacuated from Afghanistan during Operation Allies Refuge. Multidrug-resistant isolates collected from 80 patients carried an array of antimicrobial resistance genes, including carbapenemases (blaNDM-1, blaNDM-5, and blaOXA-23) and 16S methyltransferases (rmtC and rmtF). Considering the rising transmission of antimicrobial resistance and unprecedented population displacement globally, these data are a reminder of the need for robust infection control measures and surveillance.

Keywords: Afghanistan; antimicrobial resistance; bacteria; global health; infection control; military medicine; refugees.

MeSH terms

  • Adolescent
  • Adult
  • Afghanistan / epidemiology
  • Anti-Bacterial Agents* / pharmacology
  • Anti-Bacterial Agents* / therapeutic use
  • Bacteria / drug effects
  • Bacteria / genetics
  • Bacteria / isolation & purification
  • Bacterial Infections / epidemiology
  • Bacterial Infections / microbiology
  • Child
  • Drug Resistance, Multiple, Bacterial* / genetics
  • Female
  • Hospitals, Military*
  • Humans
  • Male
  • Microbial Sensitivity Tests
  • Middle Aged
  • Refugees*
  • United States / epidemiology
  • Young Adult
  • beta-Lactamases / genetics

Substances

  • Anti-Bacterial Agents
  • beta-Lactamases