Changes Over Time in Short-Term Stroke Outcomes by Race-Ethnicity

Neurology. 2024 Dec 10;103(11):e210033. doi: 10.1212/WNL.0000000000210033. Epub 2024 Nov 12.

Abstract

Objectives: The objective of this study was to quantify trends (2008-2019) in stroke outcomes by race-ethnicity.

Methods: Patients with ischemic stroke from a population-based study were interviewed at 90 days to assess outcomes. Linear regression with multiple imputation and inverse probability weighting was used to model trends.

Results: The median age was 66 years (n = 1,449); 61% were Mexican American (MA). QOL remained stable with no race-ethnic difference in trends (p for time*race-ethnicity interaction = 0.81). Neurologic outcomes improved for MA (p < 0.01) but not non-Hispanic White (NHW) persons with stroke (p = 0.23) with no race-ethnic difference in trends (p for interaction = 0.23). For functional outcomes, trends were stable and then improved in MA persons with stroke (p for interaction = 0.01), whereas trends were stable in NHW persons with stroke (p = 0.52). For cognitive outcomes, there was little change in NHW persons with stroke (p = 0.50); in MA persons with stroke, there was improvement followed by decline and then improvement (p = 0.03). No race-ethnic differences in trends in functional (p for interaction = 0.51) or cognitive (p for interaction = 0.21) outcomes were noted.

Discussion: Outcome improvements were noted in MA but not NHW persons with stroke; race-ethnic differences were not present in 2019. Understanding factors contributing to favorable trends in MA persons may be informative for improving outcomes in all persons.

MeSH terms

  • Aged
  • Aged, 80 and over
  • Female
  • Humans
  • Ischemic Stroke* / ethnology
  • Ischemic Stroke* / therapy
  • Male
  • Mexican Americans
  • Middle Aged
  • Quality of Life
  • Treatment Outcome
  • White