Recent developments in difunctionalization of unsaturated hydrocarbons with organosilicon reagents

Org Biomol Chem. 2024 Nov 13. doi: 10.1039/d4ob01471e. Online ahead of print.

Abstract

Organosilicon compounds have attracted considerable attention because of their special biological activities. Direct difunctionalization of unsaturated hydrocarbons with organosilicon reagents for the efficient construction of synthetically valuable silicon-functionalized compounds are featured with a high step and atom economy, which could form carbon-silicon/carbon-carbon bonds or carbon-silicon/carbon-hetero bonds in one step. This review summarizes the recent advances on this topic based on different unsaturated hydrocarbons along with typical examples and mechanisms.

Publication types

  • Review