Brain health equity and the influence of social determinants across the life cycle

Semin Fetal Neonatal Med. 2024 Nov;29(2-3):101553. doi: 10.1016/j.siny.2024.101553. Epub 2024 Nov 7.

Abstract

Social determinants of health are social, economic and environmental factors known to influence health and development of infants, children and adults. Advancing equity in brain health relies upon interdisciplinary collaboration and recognition of the impact of social determinants on brain health through the lifespan and across generations. Critical periods of fetal, infant and early childhood development encompass intrinsic genetic and extrinsic environmental influences with complex gene-environment interactions. This review discusses the influence of social determinants on the continuum of brain health from preconception and pregnancy health, through fetal, infant and childhood neurodevelopment into adulthood. Opportunities for intervention to address the social determinants of brain health across the life cycle are highlighted.

Keywords: Brain development; Fetal-neonatal; Health equity; Neonatal neurology; Social determinants of health.

Publication types

  • Review

MeSH terms

  • Brain* / growth & development
  • Brain* / physiology
  • Child
  • Child Development / physiology
  • Female
  • Health Equity
  • Humans
  • Infant
  • Infant, Newborn
  • Pregnancy
  • Social Determinants of Health*