Primary mesenchymal tumors of the prostate:18F FDG PET/CT findings

Zihao Tao; Yongkang Qiu; Zhao Chen; Wenpeng Huang; Lele Song; Aixiang Wang; Xuesong Li; Lei Kang

doi:10.1186/s13550-024-01177-4

Primary mesenchymal tumors of the prostate:¹⁸F FDG PET/CT findings

EJNMMI Res. 2024 Nov 14;14(1):109. doi: 10.1186/s13550-024-01177-4.

Authors

Zihao Tao^{1

2}, Yongkang Qiu¹, Zhao Chen¹, Wenpeng Huang¹, Lele Song¹, Aixiang Wang³, Xuesong Li⁴, Lei Kang⁵

Affiliations

¹ Department of Nuclear Medicine, Peking University First Hospital, Beijing, 100034, China.
² Department of Urology, Institute of Urology, Peking University First Hospital, Peking University, National Urological Cancer Center, Beijing, 100034, China.
³ Department of Urology Pathology, Peking University First Hospital, Beijing, 100034, China.
⁴ Department of Urology, Institute of Urology, Peking University First Hospital, Peking University, National Urological Cancer Center, Beijing, 100034, China. [email protected].
⁵ Department of Nuclear Medicine, Peking University First Hospital, Beijing, 100034, China. [email protected].

PMID: 39542970
DOI: 10.1186/s13550-024-01177-4

Abstract

Background: Primary mesenchymal tumors of the prostate are very rare, and there is no systematic report on fluorine-18-fluorodeoxyglucose positron emission tomography (¹⁸F-FDG PET/CT). The aim of this research was to characterize mesenchymal tumors of the prostate on ¹⁸F-FDG PET/CT.

Results: We included 13 patients with pathologically confirmed mesenchymal neoplasms of the prostate. The location, size, maximum standardized uptake value (SUVmax), metabolic tumor volume (MTV), total glycolysis of the lesion (TLG), pathologic findings, and available imaging study of the tumors were reviewed. Of the 13 patients (median age, 38 years; ranged from 13 to 74 years), the mean size of the tumors was 8.8 cm in diameter ranged from 5 to 16.1 cm. SUVmax ranged from 3.1 to 17.6 (mean 9.5), MTV ranged from 4.9 to 398 cm³ (mean 109 cm³) and TLG ranged from 21.3 to 1216 g (mean 96 g). The seminal vesicles, rectum, and bladder are the most commonly affected sites of invasion, while metastasis typically occurs in the bones, lungs, and lymph nodes.

Conclusions: Mesenchymal tumors of the prostate revealed large sizes and high SUVmax, MTV and TLG levels on ¹⁸F-FDG PET/CT. ¹⁸F-FDG PET/CT may be useful for accurate diagnosis, staging, and restaging, which plays an important role in the management of subsequent plans.

Abstract

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