Xylazine induces dopamine release and augments the effects of fentanyl

J Clin Invest. 2024 Nov 15;134(22):e183354. doi: 10.1172/JCI183354.

Joseph R Trinko¹, Ethan Foscue¹, Edward M Kong¹, Aakash Basu^{1

2}, Anouk M Corstens¹, Summer L Thompson¹, Alfred P Kaye^{1

2

3

4}, Jane R Taylor^{1

2

4}, Ralph J DiLeone^{1

2

4}

¹ Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut, USA.
² Interdepartmental Neuroscience Program, Yale University, New Haven, Connecticut, USA.
³ VA National Center for PTSD Clinical Neuroscience Division, West Haven, Connecticut, USA.
⁴ Wu Tsai Institute, Yale University, New Haven, Connecticut, USA.

No abstract available

Keywords: Addiction; Neuroscience.