Radiation therapy for stage IIA/IIB seminomas: Back to the future?

Radiother Oncol. 2025 Jan:202:110626. doi: 10.1016/j.radonc.2024.110626. Epub 2024 Nov 16.

Abstract

Seminoma is a highly curable disease; therefore, long-term morbidity of oncological treatment represents a crucial stake. In view of the considerable advances made in radiotherapy in the past decade, we aim to shed light on current and future strategies that hold promises for the management of stage II seminoma.

Keywords: Chemotherapy; Germ cell tumor; Protontherapy; Radio-induced malignancy; Radiotherapy; Seminoma.

MeSH terms

  • Humans
  • Male
  • Neoplasm Staging
  • Seminoma* / pathology
  • Seminoma* / radiotherapy
  • Testicular Neoplasms* / pathology
  • Testicular Neoplasms* / radiotherapy