The First Case of Felty's Syndrome Complicated by COVID-19 Infection

Yueming Li; Fanyou Zhu; Rui Wen; Tingting Hou; Rou Xie; Jiao Qin

doi:10.2147/JIR.S479377

The First Case of Felty's Syndrome Complicated by COVID-19 Infection

J Inflamm Res. 2024 Nov 14:17:8853-8860. doi: 10.2147/JIR.S479377. eCollection 2024.

Authors

Yueming Li¹, Fanyou Zhu¹, Rui Wen¹, Tingting Hou¹, Rou Xie¹, Jiao Qin¹

Affiliation

¹ Department of Rheumatology and Immunology, The Affiliated Changsha Central Hospital, Hengyang Medical School, University of South China, Changsha, Hunan, People's Republic of China.

Abstract

Felty's syndrome (FS) is an uncommon disorder with a poor prognosis, and most patients die from infections caused by neutropenia. Currently, there is no standardized treatment strategy, and treatment options are based on case reports and clinical experience. To date, no cases of FS complicated by coronavirus disease-2019 (COVID-19) have been reported. This article reports a successful case of FS complicated by COVID-19. We emphasized treating rheumatic diseases with immunosuppressive therapy at appropriate doses based on strong and effective anti-infection when co-infected.

Keywords: COVID-19; Felty’s syndrome; molnupiravir; neutropenia; rheumatoid arthritis.

Publication types

Case Reports

Grants and funding

This research was supported by the Hunan Provincial Health Commission Foundation (Grant No. 202203052625), Scientific research Project of Education Department of Hunan Province (Grant No.22A0321), Changsha guiding scientific research Program Project (Grant No.KZD21074), Changsha Central Hospital Subject of South China University (Grant No.YNKY202101), Guide project of Clinical Innovation in Hunan Province (Grant No.2021SK53410).