Automated insulin delivery systems in the treatment of diabetes: Benefits, challenges, and practical considerations in pediatric patients

Endocrinol Diabetes Nutr (Engl Ed). 2024 Dec;71(10):436-446. doi: 10.1016/j.endien.2024.11.010. Epub 2024 Nov 19.

Abstract

At present, the majority of patients with type 1 diabetes mellitus do not achieve the recommended glycemic control goals to reduce the risk of acute and chronic complications. Hybrid closed-loop systems or automated insulin infusion systems emerged as an opportunity to improve metabolic control, quality of life and reduce the psychosocial impact of type 1 diabetes. This article analyzes the evidence regarding their effectiveness and safety, the challenges they pose and best practices to optimize results when implemented in clinical practice.

Keywords: Asa cerrada; Automated delivery systems; Closed-loop; Diabetes mellitus tipo 1; Sistemas de infusión automatizada; Tratamiento; Treatment; Type 1 diabetes mellitus.

Publication types

  • Review

MeSH terms

  • Adolescent
  • Child
  • Diabetes Mellitus, Type 1* / blood
  • Diabetes Mellitus, Type 1* / drug therapy
  • Humans
  • Hypoglycemic Agents / administration & dosage
  • Hypoglycemic Agents / therapeutic use
  • Insulin Infusion Systems*
  • Insulin* / administration & dosage
  • Insulin* / therapeutic use

Substances

  • Insulin
  • Hypoglycemic Agents