Thyroid cancer is common among women of reproductive age and is a frequently occurring cancer during pregnancy, following breast cancer. Contributing factors include radiation exposure, iodine deficiency, and genetic conditions like multiple endocrine neoplasia type 2 (MEN2). Pregnancy significantly impacts thyroid function, leading to gland enlargement and altered thyroid stimulating hormone (TSH) levels due to hormonal changes, including elevated human chorionic gonadotropin (hCG) and estrogen. When differentiated thyroid cancer (DTC), particularly papillary thyroid carcinoma (PTC), is diagnosed during pregnancy or shortly after, careful management is essential. Treatment usually involves total thyroidectomy, with radioactive iodine therapy delayed until after childbirth. A review of cases indicates that women with PTC can have successful pregnancies with close medical supervision. Despite the complexities of cancer treatment during pregnancy, outcomes for both mother and baby are generally positive. These cases emphasize the importance of a collaborative approach in managing thyroid cancer during pregnancy and highlight the need for further research to optimize treatment and outcomes for both mother and child.
Keywords: beta-hcg; maternofetal outcome; pregnancy; thyroid cancer; thyroid-stimulating hormone (tsh).
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