Glucose Control During Labour and Delivery in Type 1 Diabetes - An Update on Current Evidence

Curr Diab Rep. 2024 Nov 22;25(1):7. doi: 10.1007/s11892-024-01563-1.

Abstract

Purpose of review: To provide an update on diabetes management during labour and delivery in women with type 1 diabetes with focus on appropriate insulin administration, carbohydrate supply and use of diabetes technology to support safe delivery and neonatal well-being.

Recent findings: During active labour and elective cesarean section capillary blood glucose monitoring or continuous glucose monitoring at least hourly is recommended. Infusion with isotonic (5%) glucose can be given with adjustable infusion rate to address maternal carbohydrate requirements and to prevent maternal hypoglycemia. Subcutaneous insulin administration with multiple injections or insulin pump therapy is considered at least as safe and efficient as intravenous administration to obtain tight glycemic targets. Automated insulin delivery via insulin pump can be continued during labour and delivery. Diabetes management during labour and delivery involves intensive glucose monitoring, adequate insulin administration and carbohydrate administration to support safe delivery and neonatal well-being.

Keywords: Delivery; Hypoglycemia; Insulin pump systems; Labour; Multiple daily injections; Type 1 diabetes.

Publication types

  • Review

MeSH terms

  • Blood Glucose / analysis
  • Blood Glucose / metabolism
  • Delivery, Obstetric
  • Diabetes Mellitus, Type 1* / blood
  • Diabetes Mellitus, Type 1* / drug therapy
  • Female
  • Glycemic Control / methods
  • Humans
  • Hypoglycemic Agents / administration & dosage
  • Hypoglycemic Agents / therapeutic use
  • Insulin / administration & dosage
  • Insulin / therapeutic use
  • Insulin Infusion Systems
  • Labor, Obstetric*
  • Pregnancy
  • Pregnancy in Diabetics* / blood
  • Pregnancy in Diabetics* / drug therapy

Substances

  • Blood Glucose
  • Insulin
  • Hypoglycemic Agents