Biomechanical Evaluation of a Novel Ceramic Implant for Canine Cranial Cruciate Ligament Rupture Treatment: A Finite Element Analysis Approach

Animals (Basel). 2024 Nov 15;14(22):3296. doi: 10.3390/ani14223296.

Abstract

This research investigates the biomechanical effects of a novel ceramic implant for the treatment of canine cranial cruciate ligament rupture (CCLR) based on the tibial tuberosity advancement (TTA) method using finite element analysis (FEA). A 3D FEA of the tibiofemoral joint simulating the applied forces (44.5% of body weight) during the mid-stance phase (joint angle 135°) of the dog's stride was performed. Three conditions were considered for each joint: the physiological condition, the pathological condition with CCLR and the restored condition after TTA. Eight cadavers were used to create fifteen paired knee joints. The results showed significant differences in the forces that could be measured in the patellar tendon (PT) and in the cranial displacement of the tibial tuberosity between the conditions. The PT forces increased in the pathological state and continued to increase in the restored state, while the cranial displacement of the tibial tuberosity increased in the pathological state and decreased again in the restored state. Correlation analyses revealed significant correlations between PT forces, body weight and cranial displacement. The FEA provides initial insights into the force distribution and functionality of the ceramic implant. However, further testing is required to validate reliability and evaluate the efficacy of the implant.

Keywords: biomechanics; canine orthopaedics; ceramic implant; cranial cruciate ligament rupture; finite element analysis; tibial tuberosity advancement.

Grants and funding

This research was funded by the Central Innovation Programme for SMEs (Zentrales Innovationsprogramm Mittelstand-ZIM) via AiF by the Federal Ministry for Economic Affairs and Climate Action (Germany) (BMWK), based on a resolution of the German Parliament. (grant number KK5066601BM0; project acronym: KrOpe3D).