Pulmonary cryptococcosis associated with Cryptococcus neoformans in an immunocompetent child

Pediatr Pulmonol. 2025 Jan;60(1):e27368. doi: 10.1002/ppul.27368. Epub 2024 Nov 27.

Abstract

We report a pediatric case of pulmonary cryptococcosis caused by Cryptococcus neoformans in an immunocompetent child. Although the patient presented with mild clinical symptoms, pulmonary imaging revealed severe abnormalities. The diagnosis was confirmed through fungal culture of bronchoalveolar lavage fluid and detection of serum cryptococcal antigen. An appropriate and adequately administered course of antifungal treatment led to a favorable prognosis.

Keywords: Cryptococcus neoformans; immunocompetent child; pulmonary; pulmonary cryptococcosis.

Publication types

  • Case Reports
  • Letter

MeSH terms

  • Antifungal Agents* / therapeutic use
  • Antigens, Fungal / analysis
  • Antigens, Fungal / blood
  • Bronchoalveolar Lavage Fluid / microbiology
  • Child
  • Cryptococcosis* / diagnosis
  • Cryptococcosis* / drug therapy
  • Cryptococcus neoformans* / isolation & purification
  • Humans
  • Immunocompetence*
  • Lung Diseases, Fungal* / diagnosis
  • Lung Diseases, Fungal* / diagnostic imaging
  • Lung Diseases, Fungal* / drug therapy
  • Lung Diseases, Fungal* / microbiology
  • Male
  • Tomography, X-Ray Computed

Substances

  • Antifungal Agents
  • Antigens, Fungal

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