Management of Myelodysplastic Syndrome in Pregnant Patients: Treatment Approaches and Considerations

Erin McDonald; David M Swoboda

doi:10.1053/j.seminhematol.2024.11.001

Management of Myelodysplastic Syndrome in Pregnant Patients: Treatment Approaches and Considerations

Semin Hematol. 2024 Dec;61(6):465-469. doi: 10.1053/j.seminhematol.2024.11.001. Epub 2024 Nov 20.

Authors

Erin McDonald¹, David M Swoboda²

Affiliations

¹ Tampa General Hospital Cancer Institute, Tampa, FL, USA.
² Tampa General Hospital Cancer Institute, Tampa, FL, USA. Electronic address: [email protected].

PMID: 39603906
DOI: 10.1053/j.seminhematol.2024.11.001

Abstract

Myelodysplastic Syndromes (MDS) and pregnancy are a rare combination and as such, there remains limited recommendations for treatment of this special population of patients. In this paper, we present 2 clinical cases to provide theoretical decision making for management of pregnancy in the setting of MDS based on expert opinion and accumulation of available data. We outline additional considerations and workup to help guide providers in successful management of this complex clinical dilemma.

Keywords: Anemia; Cytopenia; Myelodysplastic syndrome; Pregnancy; Thrombocytopenia.

Publication types

Case Reports
Review

MeSH terms

Disease Management
Female
Humans
Myelodysplastic Syndromes* / diagnosis
Myelodysplastic Syndromes* / therapy
Pregnancy
Pregnancy Complications, Neoplastic* / diagnosis
Pregnancy Complications, Neoplastic* / therapy