Discovering Phlebia acerina for efficient degradation of bisphenol S and insights into its degradation mechanism

Mingdong Chang; Ji-Hang Jiang; Jianqiao Wang; Ru Yin; Qiaoyu Li; NaNa Wang; Pengfei Xiao; Li-Wei Zhou; Tangfu Xiao

doi:10.1016/j.biortech.2024.131912

Discovering Phlebia acerina for efficient degradation of bisphenol S and insights into its degradation mechanism

Bioresour Technol. 2024 Nov 28:418:131912. doi: 10.1016/j.biortech.2024.131912. Online ahead of print.

Authors

Mingdong Chang¹, Ji-Hang Jiang², Jianqiao Wang³, Ru Yin¹, Qiaoyu Li¹, NaNa Wang¹, Pengfei Xiao⁴, Li-Wei Zhou⁵, Tangfu Xiao⁶

Affiliations

¹ Key Laboratory for Water Quality and Conservation of the Pearl River Delta, Ministry of Education, School of Environmental Science and Engineering, Guangzhou University, Guangzhou 510006, China.
² State Key Laboratory of Mycology, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China.
³ Key Laboratory for Water Quality and Conservation of the Pearl River Delta, Ministry of Education, School of Environmental Science and Engineering, Guangzhou University, Guangzhou 510006, China. Electronic address: [email protected].
⁴ College of Forestry, Northeast Forestry University, Harbin 150040, China.
⁵ State Key Laboratory of Mycology, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China. Electronic address: [email protected].
⁶ Key Laboratory for Water Quality and Conservation of the Pearl River Delta, Ministry of Education, School of Environmental Science and Engineering, Guangzhou University, Guangzhou 510006, China; State Key Laboratory of Geohazard Prevention and Geoenvironment Protection, Chengdu University of Technology, Chengdu 610059, China.

PMID: 39615765
DOI: 10.1016/j.biortech.2024.131912

Abstract

Bisphenol S (BPS) has attracted much attention as an emerging hazardous contaminant due to its endocrine disruption and oncogenic effects. Although white-rot fungi have remarkable bioremediation capabilities for some bisphenols, little is known about their performance in BPS degradation. In this study, the newly discovered Phlebia acerina S-LWZ20190614-6 exhibited high capacity to degrade BPS. To further explore the mechanism of BPS degradation by P. acerina S-LWZ20190614-6, the whole-genome background and degradation pathways were investigated. Five low-toxicity metabolites were detected during the BPS biodegradation process, and a strong correlation was found between this biodegradation process and the interactions between BPS and ligninolytic enzymes. Moreover, transcriptomic analysis revealed that genes related to DNA replication and repair, ABC transporters, and fatty acid metabolism were involved in this BPS degradation process. Overall, this study provides insights into the achievement of BPS biodegradation by white-rot fungi.

Keywords: Biodegradation; Bisphenols; Ligninolytic enzymes; Multiomics analyses; White-rot fungi.