Rapid Onsite Evaluation: A Prospective Observational Study of Endobronchial Ultrasound-Guided Transbronchial Needle Aspirates to Expedite Diagnosis

Br J Biomed Sci. 2024 Nov 14:81:12938. doi: 10.3389/bjbs.2024.12938. eCollection 2024.

Abstract

Biomedical scientists (BMS) can report sample adequacy during EBUS TBNA using rapid on-site evaluation (ROSE). Despite being able to report exfoliative samples such as pleural fluid cytology and bronchial washings, they are usually not permitted to offer a preliminary diagnostic impression of EBUS TBNA samples. Experienced biomedical scientists can provide a reliable diagnostic impression during ROSE for EBUS samples, with sensitivity and specificity comparable to cytopathologist reporting. This work represents an advance in biomedical science because it provides evidence a BMS can safely and accurately provide a real time cytopathological impression from EBUS TBNA sampling, which could positively impact patient pathways.

Keywords: EBUS; adequacy; cytopathologist; lung cancer pathway; rapid-onsite evaluation (ROSE).

Publication types

  • Observational Study

MeSH terms

  • Adult
  • Aged
  • Bronchoscopy / methods
  • Endoscopic Ultrasound-Guided Fine Needle Aspiration* / methods
  • Female
  • Humans
  • Lung Neoplasms / diagnosis
  • Lung Neoplasms / diagnostic imaging
  • Lung Neoplasms / pathology
  • Male
  • Middle Aged
  • Prospective Studies
  • Rapid On-site Evaluation
  • Sensitivity and Specificity

Grants and funding

The author(s) declare that financial support was received for the research, authorship, and/or publication of this article. Publication supported by the Frimley Health Charity.