A stage dependent combined procedure of surgery and radiotherapy should be performed in penile carcinoma. Including all stages a local tumor control rate of 85% can be achieved if a radiation dosage of at least 55-60 Gy is applied. Surgery of recurrences is not impaired after radiotherapy. Prophylactic irradiation of regional lymph nodes should be performed in all tumors with more than T2 extension and in tumors located at the base of the Penis. Carcinoma of the urethra in general should be treated primarily by surgery, but in advanced tumors and in old patients a combined procedure of surgery and irradiation can be recommended. Prophylactic irradiation of the regional lymph nodes should be performed in tumors located in the proximal part of the urethra. In certain cases of infiltration of the bladder iliac lymph nodes should be irradiated as well. The results of 63 patients with penile carcinoma and 13 cases of carcinoma of the urethra are reported.