Laticifers as in vivo plant cell factories for therapeutic proteins

Trends Biotechnol. 2024 Dec 3:S0167-7799(24)00327-5. doi: 10.1016/j.tibtech.2024.11.014. Online ahead of print.

Abstract

The demand for therapeutic proteins is growing annually. Novel approaches for the production of these molecules on a large scale are necessary, especially in plants. Plant laticifers could help provide an in vivo cell system for protein production expression that can reduce costs of production and downstream processing.

Keywords: biopharming; latex; pharmaceutics; plant transgenesis.