On-Treatment Change in d-Dimer Is Associated With Differential Outcomes Among Therapeutic Dose Heparin-Treated Noncritically Ill Patients Hospitalized for COVID-19
Arterioscler Thromb Vasc Biol
.
2025 Jan;45(1):162-164.
doi: 10.1161/ATVBAHA.124.321108.
Epub 2024 Dec 5.
Authors
Lana Wahid
1
2
,
Joshua D Froess
3
,
Thomas L Ortel
4
5
6
,
Ryan Zarychanski
7
,
Jeffrey S Berger
8
,
Mary Cushman
9
10
,
Derek C Angus
11
,
Valerie Renard
12
,
Parisa Farahani
1
,
Steven Webb
13
,
Anna Heath
14
15
,
Lucas C Godoy
16
17
,
Michael E Farkouh
18
,
Judith S Hochman
8
,
Matthew D Neal
#
19
,
Patrick R Lawler
#
20
21
22
Affiliations
1
Department of Medicine, Carilion Clinic, Roanoke, VA (L.W., P.F.).
2
Department Internal of Medicine, Virginia Tech Carilion School of Medicine, Roanoke (L.W.).
3
Department of Epidemiology, School of Public Health (J.D.F.), University of Pittsburgh, PA.
4
Division of Hematology (T.L.O.), Duke University, Durham, NC.
5
Department of Medicine (T.L.O.), Duke University, Durham, NC.
6
Department of Pathology (T.L.O.), Duke University, Durham, NC.
7
University of Manitoba and CancerCare Manitoba, Canada (R.Z.).
8
Department of Medicine, New York University Grossman School of Medicine (J.S.B., J.S.H.).
9
Departments of Medicine (M.C.), Larner College of Medicine at the University of Vermont, Burlington.
10
Pathology and Laboratory Medicine (M.C.), Larner College of Medicine at the University of Vermont, Burlington.
11
Division of Critical Care Medicine (D.C.A.), University of Pittsburgh, PA.
12
Hospital Medicine, Department of Medicine, Duke University Health, Durham, NC (V.R.).
13
Australian and New Zealand Intensive Care Research Centre, Monash University, Clayton, VIC, Australia (S.W.).
14
Child Health Evaluative Sciences, The Hospital for Sick Children, Toronto, ON, Canada (A.H.).
15
Division of Biostatistics, Dalla Lana School of Public Health (A.H.), University of Toronto, ON, Canada.
16
Peter Munk Cardiac Centre (L.C.G.), University of Toronto, ON, Canada.
17
Institute of Health Policy Management and Evaluation (L.C.G.), University of Toronto, ON, Canada.
18
Division of Cardiology, Cedars-Sinai Health System, Los Angeles, CA (M.E.F.).
19
Department of Surgery (M.D.N.), University of Pittsburgh, PA.
20
Division of Cardiology (P.R.L.), University of Toronto, ON, Canada.
21
Division of Critical Care Medicine (P.R.L.), University of Toronto, ON, Canada.
22
Division of Cardiology, McGill University Health Centre, Montreal, QC, Canada (P.R.L.).
#
Contributed equally.
PMID:
39633573
DOI:
10.1161/ATVBAHA.124.321108
No abstract available
Keywords:
COVID-19; critical care; heparin; precision medicine; thromboinflammation.
Publication types
Letter
Associated data
ClinicalTrials.gov/NCT04372589