Rescue Transcatheter Native Aortic Valve Closure to Treat Severe Aortic Regurgitation in a Patient With Single Ventricular Physiology and Decompensated Heart Failure

Catheter Cardiovasc Interv. 2025 Jan;105(1):187-192. doi: 10.1002/ccd.31342. Epub 2024 Dec 5.

Abstract

Semilunar valve regurgitation in single ventricular physiology is rare but portends a poor prognosis. Medical therapy is often ineffective particularly in the context of structural valve abnormality, and surgical valve repair or replacement can be associated with poor outcomes. We report an innovative use of a highly occlusive and conformable Gore Septal Occluder for transcatheter treatment of severe native aortic regurgitation in a symptomatic patient with hypoplastic left heart syndrome and severe systemic right ventricular dysfunction, resulting in safe and complete occlusion of the aortic regurgitant orifice and clinical benefit.

Publication types

  • Case Reports

MeSH terms

  • Aortic Valve Insufficiency* / diagnostic imaging
  • Aortic Valve Insufficiency* / etiology
  • Aortic Valve Insufficiency* / physiopathology
  • Aortic Valve Insufficiency* / surgery
  • Aortic Valve* / diagnostic imaging
  • Aortic Valve* / physiopathology
  • Aortic Valve* / surgery
  • Cardiac Catheterization* / instrumentation
  • Echocardiography, Doppler, Color
  • Heart Failure* / diagnosis
  • Heart Failure* / etiology
  • Heart Failure* / physiopathology
  • Heart Failure* / therapy
  • Hemodynamics
  • Humans
  • Hypoplastic Left Heart Syndrome / physiopathology
  • Hypoplastic Left Heart Syndrome / surgery
  • Male
  • Prosthesis Design
  • Recovery of Function
  • Septal Occluder Device*
  • Severity of Illness Index*
  • Treatment Outcome
  • Ventricular Dysfunction, Right / diagnostic imaging
  • Ventricular Dysfunction, Right / etiology
  • Ventricular Dysfunction, Right / physiopathology
  • Ventricular Dysfunction, Right / therapy
  • Ventricular Function, Right