A new species of pilumnid crab, Pseudolitochira spinosa sp. nov., is described from a seagrass bed in Panglao, Bohol, central Philippines. The new species is morphologically most similar to P. maenosonoi Ng & Clark, 2022, from Okinawa, Japan, in its proportionately wide carapace, but can be distinguished by the possession of prominent anterolateral spines, distinct spines on the merus of the cheliped and the presence of a well-developed sharp tooth on the inner angle of the cheliped carpus. The taxonomy of the poorly known P. setosa (A. Milne-Edwards, 1873) from New Caledonia is also discussed and a lectotype selected.