Cornual Pregnancy as a Rare Entity of Ectopic Pregnancy After Assisted Reproductive Therapy-Embryo Transfer (ART-ET): A Case Report

Clin Case Rep. 2024 Dec 6;12(12):e9708. doi: 10.1002/ccr3.9708. eCollection 2024 Dec.

Abstract

Cornual pregnancy, a rare and life-threatening form of ectopic pregnancy, poses significant diagnostic and therapeutic challenges due to its deep implantation in the uterus. This report presents a case of a 31-year-old woman with a history of assisted reproductive technology (ART) and prior salpingectomy, who was diagnosed with a right cornual pregnancy following embryo transfer. The patient experienced lower abdominal pain and was found to have an enlarged uterus on ultrasonography. Early diagnosis via three-dimensional transvaginal ultrasonography enabled timely intervention, preventing rupture and severe hemorrhage. Surgical management involved a combined hysteroscopy and minilaparotomy to resect the cornual pregnancy. Histopathology confirmed the diagnosis, and the patient's recovery was uneventful. Elective cesarean section at 36-37 weeks was advised for future pregnancies to prevent uterine rupture.

Keywords: cornual pregnancy; embryo transfer; in vitro fertilization (IVF); salpingectomy.