Aspergillus causes a range of diseases in patients with immunodeficiency or underlying pulmonary diseases. Aspergillus-specific immunoglobulin G antibody (Asp-IgG) is produced in response to Aspergillus pathopoiesis. Currently, Asp-IgG is included in the diagnostic criteria for chronic pulmonary aspergillosis (CPA) and allergic bronchopulmonary aspergillosis (ABPA). In recent years, some researches have proved that Asp-IgG also has important diagnostic value for non-neutropenic patients with invasive pulmonary aspergillosis (IPA). This review summarized the progress of Asp-IgG in the management of different types of pulmonary aspergillosis, and the advantages of rapid detection methods for Asp-IgG.
曲霉可在免疫功能缺陷或者有肺部基础疾病的患者中引起多种类型的疾病。曲霉特异性免疫球蛋白G抗体（Asp-IgG）在曲霉致病过程中产生。目前相关指南已将Asp-IgG纳入慢性肺曲霉病和变应性支气管肺曲霉病的诊断标准中。近年来有研究报道Asp-IgG对非中性粒细胞缺乏侵袭性肺曲霉病同样也有较高的诊断价值。现将Asp-IgG在肺曲霉病诊断和监测治疗反应中的临床应用进展以及Asp-IgG快速检测技术的应用价值做一综述。.