Enhanced sensing of dinotefuran in foods based on BC/ZnCo MOF@PBA nano-enzyme induced MIECL sensor

Shijie Dai; Haoran Chen; Yongxing Zhang; Lan Zhang; Tao Liu; Chun Wu; Mengmeng Sun; Gehong Su; Jianshan Ye; Yanying Wang; Hanbing Rao; Zhiwei Lu

doi:10.1016/j.foodchem.2024.142339

Enhanced sensing of dinotefuran in foods based on BC/ZnCo MOF@PBA nano-enzyme induced MIECL sensor

Food Chem. 2024 Dec 6:467:142339. doi: 10.1016/j.foodchem.2024.142339. Online ahead of print.

Authors

Shijie Dai¹, Haoran Chen², Yongxing Zhang³, Lan Zhang², Tao Liu⁴, Chun Wu², Mengmeng Sun², Gehong Su², Jianshan Ye⁵, Yanying Wang², Hanbing Rao⁶, Zhiwei Lu⁷

Affiliations

¹ College of Science, Sichuan Agricultural University, Xin Kang Road, Yucheng District, Ya'an 625014, PR China; College of Forestry, Sichuan Agricultural University, Hui Ming Road, Chengdu 611130, PR China.
² College of Science, Sichuan Agricultural University, Xin Kang Road, Yucheng District, Ya'an 625014, PR China.
³ Anhui Province Key Laboratory of Intelligent Computing and Applications, Huaibei Normal University, Huaibei, Anhui 235000, PR China.
⁴ College of Information Engineering, Sichuan Agricultural University, Xin Kang Road, Yucheng District, Ya'an 625014, PR China. Electronic address: [email protected].
⁵ School of Chemistry and Chemical Engineering, South China University of Technology, Guangzhou 510641, PR China.
⁶ College of Science, Sichuan Agricultural University, Xin Kang Road, Yucheng District, Ya'an 625014, PR China. Electronic address: [email protected].
⁷ College of Science, Sichuan Agricultural University, Xin Kang Road, Yucheng District, Ya'an 625014, PR China. Electronic address: [email protected].

PMID: 39657484
DOI: 10.1016/j.foodchem.2024.142339

Abstract

Natural enzymes can increase the signal of electrochemiluminescence. However, they are expensive and environmentally demanding. Here, the hollow prussian blue analogues decorated and biomass-derived carbon doped ZnCo metal-organic framework nano-enzyme was designed via self-assembly method. The BC/ZnCo MOF@PBA with peroxidase activity boosts the ECL intensity by catalyzing H₂O₂ to produce more free radicals as intermediates in the ECL reaction. Then, the molecularly imprinted polymer was synthesized by in-situ electropolymerization using o-aminophenol as the functional monomer and dinotefuran as the template molecule to form the MIECL sensor. This MIECL sensor exhibited high sensitivity for dinotefuran detection with a good linear relationship range from 0.01 μM to 100 μM, and a low detection limit of 0.0046 μM, which was better than the reported dinotefuran sensor. Additionally, this MIECL sensor has good selectivity, stability, repeatability, etc. Lastly, the MIECL sensor performed well in the fruit sample detection.

Keywords: Co-reactant accelerator; Dinotefuran detection; Electrochemiluminescence; Molecularly imprinted polymers; Nano-enzyme.