Unexpected Victory: High-Risk Papillary Thyroid Cancer with Distant Metastases Shows Extraordinary Response to First RAI Treatment

J Pak Med Assoc. 2024 Dec;74(12):2202-2203. doi: 10.47391/JPMA.24-102.

Abstract

Papillary Thyroid Cancer (PTC) is the most prevalent type of differentiated thyroid cancer. Its incidence is growing worldwide although it has low death rates. Treatment includes surgery followed by radioactive iodine therapy. Patients are followed up with serum tumour markers (stimulated and unstimulated), sonographically and with iodine I-131 whole body scans. Patients with aggressive metastatic disease have worse prognosis as compared to those with localized disease. We present a case of high-risk PTC with lung metastases, who showed excellent response after the first radioactive iodine therapy.

Keywords: Thyroid cancer, lung metastases, excellent response..

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Carcinoma, Papillary / pathology
  • Carcinoma, Papillary / radiotherapy
  • Humans
  • Iodine Radioisotopes* / therapeutic use
  • Lung Neoplasms* / pathology
  • Lung Neoplasms* / radiotherapy
  • Lung Neoplasms* / secondary
  • Male
  • Thyroid Cancer, Papillary* / pathology
  • Thyroid Cancer, Papillary* / radiotherapy
  • Thyroid Cancer, Papillary* / secondary
  • Thyroid Cancer, Papillary* / therapy
  • Thyroid Neoplasms* / pathology
  • Thyroid Neoplasms* / radiotherapy
  • Thyroidectomy
  • Treatment Outcome

Substances

  • Iodine Radioisotopes
  • Iodine-131