The medical data of 10 patients with undifferentiated pleomorphic sarcoma (UPS) from the head and neck at Henan Cancer Hospital from January 2013 to January 2023 were retrospectively analyzed. There were 5 males and 5 females, aged (57.6±13.1) years. The lesions were located in the nasal cavity (one case), the paranasal sinuses (two cases), the parotid gland (one case), the nape (one case), the thyroid gland (one case), and the neck (four cases), respectively. Eight patients underwent surgical intervention, all of whom received adjuvant therapies, including post-surgery radiotherapy and chemotherapy. One patient declined treatment due to personal reasons, and another patient lost the opportunity for surgery and received chemotherapy instead. The follow-up period ranged from 1 to 128 months, with a median follow-up time of 31 (11, 101) months. During the follow-up period, there were a total of four deaths: two due to recurrence after surgery, one due to discontinuing treatment, and one due to severe illness that responded poorly to treatment.The remaining 6 patients who received surgery combined with radiotherapy or chemotherapy showed no recurrence. To sum up, UPS of the head and neck is rare, exhibits a high recurrence rate, and has a poor prognosis. Surgical resection combined with radiotherapy is an important treatment modality.
回顾性分析2013年1月至2023年1月河南省肿瘤医院收治的10例头颈部未分化多形性肉瘤（UPS）患者临床资料，男5例，女5例，年龄（57.6±13.1）岁。病变位于鼻腔1例，鼻窦2例，腮腺1例，项部1例，甲状腺1例，颈部4例。8例患者接受手术治疗，同时均接受术后辅助治疗如放疗或化疗，1例患者因个人原因放弃治疗，1例患者无手术机会给予化疗。随访时间31（11，101）个月，随访期间共4例死亡，2例因术后复发死亡，1例因放弃治疗死亡，1例因疾病严重治疗效果不佳死亡；其余6例患者给予手术加放疗或化疗后随访至今无复发。头颈部UPS临床少见，复发率较高，预后差，手术切除和放疗是重要治疗手段。.