Novel insights into Bacillus thuringiensis: Beyond its role as a bioinsecticide

Gholamreza Salehi Jouzani; Reza Sharafi; Leandris Argentel-Martínez; Ofelda Peñuelas-Rubio; Ceyda Ozkan; Bengisu Incegul; Rana Goksu; Zehra Hayta; Deniz Yilki; Beyza Yazici; Vildan Hancer; Estibaliz Sansinenea; Jae-Ho Shin; A El-Shabasy; Ugur Azizoglu

doi:10.1016/j.resmic.2024.104264

Novel insights into Bacillus thuringiensis: Beyond its role as a bioinsecticide

Res Microbiol. 2024 Dec 13:104264. doi: 10.1016/j.resmic.2024.104264. Online ahead of print.

Authors

Affiliations

¹ Microbial Biotechnology Department, Agricultural Biotechnology Research Institute of Iran (ABRII), Agricultural Research, Education and Extension Organization (AREEO), Karaj, Iran. Electronic address: [email protected].
² National Center for Genetic Resources of Agriculture and Natural Resources, Agricultural Research, Education and Extension Organization (AREEO), Fahmideh Blvd, Karaj, Iran.
³ Department of Engineering, National Technological Institute of Mexico/Technological Institute of Yaqui Valley, Bacum, Sonora, Mexico.
⁴ Faculty of Life and Natural Sciences, Molecular Biology and Genetics Department, Abdullah Gul University, Kayseri, Turkiye.
⁵ Facultad de Ciencias Químicas, Benemérita Universidad Autónoma de Puebla. C.P. 72570. Puebla, Pue. Mexico.
⁶ School of Applied Biosciences, College of Agriculture and Life Sciences, Kyungpook National University, Daegu, 41566, Republic of Korea.
⁷ Department of Biology, College of Science, Jazan University, P.O. Box. 114, Jazan 45142, Kingdom of Saudi Arabia.
⁸ Department of Crop and Animal Production, Safiye Cikrikcioglu Vocational College, Kayseri University, Kayseri, Türkiye; Genome and Stem Cell Research Center, Erciyes University, Kayseri, Türkiye. Electronic address: [email protected].

PMID: 39675400
DOI: 10.1016/j.resmic.2024.104264

Abstract

This review explores the diverse applications of Bacillus thuringiensis (Bt) beyond its traditional role as a bioinsecticide. Bt produces a variety of compounds with distinct chemical structures and biological activities. These include antimicrobial agents effective against plant pathogens and bioactive compounds that promote plant growth through the production of siderophores, hormones, and enzymes. Additionally, Bt's industrial potential is highlighted, encompassing biofuel production, bioplastics, nanoparticle synthesis, food preservation, anticancer therapies, and heavy metal bioremediation. This critical analysis emphasizes recent advancements and applications, providing insights into Bt's role in sustainable agriculture, biotechnology, and environmental management.

Keywords: Anticancer activities; Bacillus thuringiensis; Bioplastic; Food preservation; Nanoparticles biosynthesis; Plant growth-promoting bacteria (PGPB).

Publication types

Review