Autism spectrum disorder is one of the most common neurodevelopmental conditions diagnosed in children. Most autism research, intervention, and policy focus exclusively on this condition in childhood, but autism often persists across the life course. This narrative review leverages data from 115 participants first diagnosed with autism between ages 2 and 3 years and subsequently followed for 3 decades (Mage = 30.93 years, SD = 3.41) to highlight key aspects of adult life and experiences for autistic individuals identified in early childhood. Compared to other autism samples, the participants described here are relatively diverse: 20% are Black or mixed race; 13% are female; 43% reside in Census-designated rural locations; and 37% have a primary caregiver without a college degree. Fifty participants have average cognitive abilities (mean intellectual quotient [mIQ] = 98.8, SD = 19.3) and are verbally fluent; the remaining 65 have an intellectual disability (mIQ = 28.5, SD = 17.7) and/or are minimally verbal. In some ways, the adult experiences of autistic individuals are quite distinct from those of the general population, but important similarities exist also, particularly related to quality of life. As the number of autistic adults continues to rise, and increasing numbers of autistic adults seek out clinical and community services, high-quality research and clinical services focused on this population should be a priority for psychological science and practice. (PsycInfo Database Record (c) 2024 APA, all rights reserved).