Bioactive Properties of Microencapsulated Anthocyanins from Vaccinium floribundum and Rubus glaucus

Molecules. 2024 Nov 21;29(23):5504. doi: 10.3390/molecules29235504.

Abstract

Anthocyanins, widely recognized for their antioxidant properties and potential health benefits, are highly susceptible to degradation due to environmental factors such as light, temperature, and pH leading to reduced bioavailability and efficacy. Microencapsulation, which involves entrapment in a matrix to enhance stability and bioavailability. This study aims to investigate the bioactive properties of microencapsulated anthocyanins derived from Vaccinium floribundum (Andean blueberry) and Rubus glaucus (Andean blackberry). The extracts from V. floribundum and R. glaucus were microencapsulated using maltodextrin as the carrier agent due to its film-forming properties and effectiveness in stabilizing sensitive compounds through a spray-drying process. The microcapsules were characterized using Fourier Transform Infrared Spectroscopy (FTIR) and Scanning Electron Microscopy (SEM) to assess their chemical and morphological properties. The biological activities of these microencapsulated anthocyanins were evaluated using in vitro assays for their antibacterial, antioxidant, and anti-inflammatory effects. The results indicated enhanced bioactivity of the microencapsulated anthocyanins, suggesting their potential use in developing functional foods and pharmaceuticals. This study provides valuable insights into the effectiveness of microencapsulation in preserving anthocyanins' functional properties and enhancing their health-promoting effects, highlighting the potential for application in the food and pharmaceutical industries.

Keywords: SDG 3; anthocyanins; antibacterial; antioxidant activity; antitumoral activity; good health and well-being; microencapsulation; phenolic compounds.

MeSH terms

  • Animals
  • Anthocyanins* / chemistry
  • Anthocyanins* / pharmacology
  • Anti-Bacterial Agents / chemistry
  • Anti-Bacterial Agents / pharmacology
  • Anti-Inflammatory Agents / chemistry
  • Anti-Inflammatory Agents / pharmacology
  • Antioxidants* / chemistry
  • Antioxidants* / pharmacology
  • Capsules
  • Drug Compounding
  • Plant Extracts* / chemistry
  • Plant Extracts* / pharmacology
  • Polysaccharides / chemistry
  • Polysaccharides / pharmacology
  • Rubus* / chemistry
  • Spectroscopy, Fourier Transform Infrared
  • Vaccinium* / chemistry

Substances

  • Anthocyanins
  • Antioxidants
  • Plant Extracts
  • Anti-Bacterial Agents
  • Anti-Inflammatory Agents
  • Polysaccharides
  • Capsules
  • maltodextrin

Grants and funding

This research received no external funding.