Trends in ovarian cancer net survival in a northeastern Brazilian state (1996-2017)

Brenda Evelin Barreto da Silva; Pamela Minicozzi; Veronica Di Carlo; Naomi Ssenyonga; Fatima Khan Baloch; Melissa Matz; Michel P Coleman; Claudia Allemani; Carlos Anselmo Lima

doi:10.1016/j.canep.2024.102720

Trends in ovarian cancer net survival in a northeastern Brazilian state (1996-2017)

Cancer Epidemiol. 2024 Dec 16:94:102720. doi: 10.1016/j.canep.2024.102720. Online ahead of print.

Authors

Brenda Evelin Barreto da Silva¹, Pamela Minicozzi², Veronica Di Carlo³, Naomi Ssenyonga⁴, Fatima Khan Baloch⁵, Melissa Matz⁶, Michel P Coleman⁷, Claudia Allemani⁸, Carlos Anselmo Lima⁹

Affiliations

¹ Health Sciences Graduate Program, Federal University of Sergipe, Aracaju, Sergipe, Brazil. Electronic address: [email protected].
² Cancer Survival Group, Faculty of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, UK. Electronic address: [email protected].
³ Cancer Survival Group, Faculty of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, UK. Electronic address: [email protected].
⁴ Cancer Survival Group, Faculty of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, UK. Electronic address: [email protected].
⁵ Cancer Survival Group, Faculty of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, UK. Electronic address: [email protected].
⁶ Cancer Survival Group, Faculty of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, UK. Electronic address: [email protected].
⁷ Cancer Survival Group, Faculty of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, UK. Electronic address: [email protected].
⁸ Cancer Survival Group, Faculty of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, UK. Electronic address: [email protected].
⁹ Health Sciences Graduate Program, Federal University of Sergipe, Aracaju, Sergipe, Brazil; Aracaju Cancer Registry, Aracaju, Sergipe, Brazil; University Hospital, Ebserh, Federal University of Sergipe, Aracaju, Sergipe, Brazil. Electronic address: [email protected].

PMID: 39689510
DOI: 10.1016/j.canep.2024.102720

Abstract

Background: Ovarian cancer survival in low- and middle-income countries is lower than in high-income countries, due to disparities in healthcare access and socioeconomic factors. This study aimed to describe trends in ovarian cancer survival in Sergipe, Northeast Brazil, by histological group.

Methods: We analysed data on 948 women aged 15-99 years diagnosed with a cancer of the ovary between 1996 and 2017, in Sergipe, Brazil. One- and five-year net survival were estimated by histological group and calendar periods of diagnosis (1996-1999, 2000-2004, 2005-2009, 2010-2014, 2015-2017) using the Pohar-Perme estimator. Survival estimates were age-standardised using International Cancer Survival Standard weights.

Results: Between 1996 and 2017, one-year and five-year net survival for ovarian cancer were 63.4 % and 37.4 %, respectively. Five-year net survival trends increased from 30.9 % (2000-2004) to 46.8 % (2015-2017). Epithelial type I tumours comprised roughly a quarter of cases, while type II tumours constituted over half. Both types exhibited similar one-year survival, ranging from 67 % to 68.5 % during 1996-2017. However, five-year net survival for type II tumours was remarkably lower at 32.5 %, compared to 52 % for type I tumours.

Conclusion: Despite a minor improvement in five-year net survival over the 22 years, survival for women with ovarian cancer remains unfavourable, particularly for those diagnosed with Type II epithelial tumours, which have remarkably lower five-year survival than Type I.

Keywords: Brazil; Epidemiology; Histology; Ovarian cancer; Population-based survival.