Complete genome sequence of Corynebacterium sp. SCR221107, encoding biosynthesis of vitamin B₁₂ isolated from the rumen fluid of Holstein dairy cows

Corynebacterium sp. SCR221107 was isolated from the rumen fluid of healthy male Holstein dairy cows from a research farm at Suncheon, Jeollanam-do, Korea. Corynebacterium sp. SCR221107 is a functional probiotic candidate that produces vitamin B₁₂. All Corynebacterium sp. SCR221107 was sequenced using the PacBio RS II and Illumina HiSeq platforms and assembled de novo. The complete genome sequence of Corynebacterium sp. SCR221107 contained one circular chromosome (3,043,024 bp) with a guanine + cytosine (GC) content of 60.1%. Annotation analysis showed the presence of 2,639 protein-coding sequences, 15 rRNA genes, and 57 tRNA genes. Genome analysis found that Corynebacterium sp. SCR221107 encodes various genes associated with vitamin B12 synthesis and transport. The genomic information provided a detailed understanding of Corynebacterium sp. SCR221107, suggesting that this isolate may have potential probiotic applications.