Periprosthetic joint infections: state-of-the-art

Thorsten Gehrke; Mustafa Citak; Javad Parvizi; Nicolaas Cyrillus Budhiparama; Mustafa Akkaya

doi:10.1007/s00402-024-05627-5

Periprosthetic joint infections: state-of-the-art

Arch Orthop Trauma Surg. 2024 Dec 18;145(1):58. doi: 10.1007/s00402-024-05627-5.

Authors

Thorsten Gehrke¹, Mustafa Citak¹, Javad Parvizi², Nicolaas Cyrillus Budhiparama³, Mustafa Akkaya^{4

5}

Affiliations

¹ Department of Orthopaedic Surgery, Helios ENDO-Klinik, Hamburg, Germany.
² Department of International Joint Center, Acibadem, Istanbul, Maslak, Turkey.
³ Department of Ortopaedic and Traumatology, Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia.
⁴ Department of Orthopaedic Surgery, Helios ENDO-Klinik, Hamburg, Germany. [email protected].
⁵ Department of Orthopaedics and Traumatology, Yuksek Ihtisas University, Faculty of Medicine, Ankara, Turkey. [email protected].

PMID: 39694911
DOI: 10.1007/s00402-024-05627-5

Abstract

In general, periprosthetic joint infection (PJI) is regarded as one of the most common complications of total joint arthroplasty (TJA) and may lead to surgical failure, revision surgery, amputation or death. Nowadays, PJI has become a global health concern, which brings a great burden to public healthcare. In addition, there are still obstacles to achieve high success rates in the prevention, diagnosis and treatment of PJI. However, promising studies are also available with the advancements in biotechnology. This article will present an overview of the current methods used in the prevention, diagnosis and management of PJI while underlining the new technologies utilized.

Keywords: Arthroplasty; Joint replacement; Periprosthetic joint infection.

Publication types

Review

MeSH terms

Arthroplasty, Replacement / adverse effects
Arthroplasty, Replacement / methods
Humans
Joint Prosthesis / adverse effects
Prosthesis-Related Infections* / etiology
Prosthesis-Related Infections* / prevention & control
Prosthesis-Related Infections* / therapy