Pushing the boundaries of radiotherapy-immunotherapy combinations: highlights from the 7th immunorad conference

Oncoimmunology. 2025 Dec;14(1):2432726. doi: 10.1080/2162402X.2024.2432726. Epub 2024 Dec 18.

Abstract

Over the last decade, the annual Immunorad Conference, held under the joint auspicies of Gustave Roussy (Villejuif, France) and the Weill Cornell Medical College (New-York, USA) has aimed at exploring the latest advancements in the fields of tumor immunology and radiotherapy-immunotherapy combinations for the treatment of cancer. Gathering medical oncologists, radiation oncologists, physicians and researchers with esteemed expertise in these fields, the Immunorad Conference bridges the gap between preclinical outcomes and clinical opportunities. Thus, it paves a promising way toward optimizing radiotherapy-immunotherapy combinations and, from a broader perspective, improving therapeutic strategies for patients with cancer. Herein, we report on the topics developed by key-opinion leaders during the 7th Immunorad Conference held in Paris-Les Cordeliers (France) from September 27th to 29th 2023, and set the stage for the 8th edition of Immunorad which will be held at Weill Cornell Medical College (New-York, USA) in October 2024.

Keywords: Cancer; FLASH radiotherapy; T cells; immune checkpoint; immunorad; immunotherapy; low-dose radiotherapy; lymph-node sparing; radiotherapy; tumor-associated macrophages.

Publication types

  • Congress

MeSH terms

  • Combined Modality Therapy
  • Humans
  • Immunotherapy* / methods
  • Neoplasms* / immunology
  • Neoplasms* / radiotherapy
  • Neoplasms* / therapy
  • Radiotherapy / methods

Grants and funding

The author(s) reported there is no funding associated with the work featured in this article. Authors acknowledge financial support from ERC advanced grant (ERC-ADG-2015 n° 694812 – Hypoximmuno. Authors also acknowledge financial support from the European Union’s Horizon research and innovation programme under grant agreement: ImmunoSABR n° 733008 (main contributor, CHAIMELEON n° 952172, EuCanImage n° 952103, IMI-OPTIMA n° 101034347, AIDAVA (HORIZON-HLTH-2021-TOOL-06) n°101057062, REALM (HORIZON-HLTH-2022-TOOL-11) n° 101095435, RADIOVAL (HORIZON-HLTH-2021-DISEASE-04-04) n°101057699, EUCAIM (DIGITAL-2022-CLOUD-AI-02) n°101100633, GLIOMATCH n° 101136670 and KWF-Alpe d’HuZes n° 13058.