Disseminated sporotrichosis with osteoarticular involvement in a patient with acquired immunodeficiency syndrome: a case report

Rev Soc Bras Med Trop. 2024 Dec 16:57:e008092024. doi: 10.1590/0037-8682-0120-2024. eCollection 2024.

Abstract

Sporotrichosis is caused by fungi belonging to the genus Sporothrix, and is generally acquired by traumatic inoculation. A 26-year-old man developed pustular lesions and a 6-kg weight loss after developing a lesion on his right hand 6 months previously. He was diagnosed with acquired human immunodeficiency syndrome (AIDS) and disseminated sporotrichosis cultures of bone and muscle biopsy and blood samples grew Sporothrix schenckii. The patient underwent reconstructive surgery and 9 months of treatment with amphotericin B and itraconazole, and showed complete wound healing and improved hand functionality. Suspicion of the disease is necessary in immunosuppressed patients living in endemic areas.

Publication types

  • Case Reports

MeSH terms

  • AIDS-Related Opportunistic Infections* / diagnosis
  • AIDS-Related Opportunistic Infections* / microbiology
  • Adult
  • Amphotericin B / therapeutic use
  • Antifungal Agents* / therapeutic use
  • Humans
  • Itraconazole / therapeutic use
  • Male
  • Sporothrix / isolation & purification
  • Sporotrichosis* / diagnosis
  • Sporotrichosis* / drug therapy

Substances

  • Antifungal Agents
  • Itraconazole
  • Amphotericin B