A Rare Case of Functional Metastatic Follicular Thyroid Carcinoma With Concomitant Thyrotoxicosis

Case Rep Endocrinol. 2024 Dec 12:2024:1398125. doi: 10.1155/crie/1398125. eCollection 2024.

Abstract

We report a case of a 60-year-old lady with metastatic follicular thyroid carcinoma (FTC) who was presented with thyrotoxicosis and heart failure symptoms after total thyroidectomy. Clinical features and investigations led to the diagnosis of functional metastatic FTC with concomitant thyrotoxicosis. Levothyroxine therapy was stopped, and she was treated with propylthiouracil (PTU) followed by serial radioiodine treatments (RAITs) with good control of thyrotoxicosis and metastases. Despite having a very high disease burden with metastatic FTC, she has been able to maintain her functional status thus far, 4.5 years after initial diagnosis.

Keywords: Graves' disease; metastatic follicular thyroid carcinoma; radioiodine treatment; thyroid stimulating hormone receptor antibody; thyroidectomy.

Publication types

  • Case Reports