Editorial for the special issue on "microbiomes in extremes of aging"

Exp Gerontol. 2025 Jan:199:112663. doi: 10.1016/j.exger.2024.112663. Epub 2024 Dec 29.

Abstract

This special issue of the Journal of Experimental Gerontology explores the dynamic interplay between microbiomes and aging-related conditions. The four selected studies highlight the role of microbiota in Alzheimer's disease, cancer immunotherapy, myocardial infarction and tryptophan metabolism, providing insights into how microbiomes influence health and disease in aging. These studies underscore the potential for microbiome-targeted interventions to mitigate aging-related disorders and improve the quality of life for older adults.

Publication types

  • Editorial
  • Introductory Journal Article

MeSH terms

  • Aging* / physiology
  • Alzheimer Disease / microbiology
  • Animals
  • Gastrointestinal Microbiome / physiology
  • Humans
  • Immunotherapy / methods
  • Microbiota / physiology
  • Myocardial Infarction / microbiology
  • Neoplasms / microbiology
  • Neoplasms / therapy
  • Quality of Life
  • Tryptophan / metabolism

Substances

  • Tryptophan