Soybeans and peanuts belong to the leguminous family and are common causes of food anaphylaxis. Symptoms range from oral allergy syndrome to severe breathing difficulties, anaphylactic shock, and even death. But the allergens causing allergies are different, and the severity of symptoms are different. Precise diagnosis at the molecular level or component-resolved diagnosis (CRD) is necessary. CRD is a technology that accurately identifies allergen proteins to help physicians personalize clinical treatment and management strategies for allergy patients. In this article, according to the European Academy of Allergy and Clinical Immunology (EAACI) issued the "Allergen Component Diagnostic Guidance Recommendation 2.0 (MAUG 2.0)", it introduces the soy and peanut allergenic components, clinical diagnosis, treatment and management, aimed at improving the accurate diagnosis and personalized treatment of soy and peanut allergy.
大豆、花生均属于豆科植物,是食物过敏性反应的常见诱因。过敏症状从口腔过敏综合征,到严重的呼吸困难、过敏性休克甚至死亡。同属豆科植物过敏患者,由于引起过敏的过敏原不同,其症状严重程度也不同,在此种情况下,基于分子水平的精准诊断或过敏原组分诊断(component-resolved diagnosis,CRD)是很有必要的。CRD是一种精准识别过敏原蛋白的技术,帮助医生为过敏患者提供个性化的脱敏治疗和管理策略。本文根据欧洲过敏和临床免疫学会(European Academy of Allergy and Clinical Immunology,EAACI)发布的《过敏原组分诊断指导建议2.0》(MAUG 2.0)解读了大豆和花生过敏原主要致敏组分识别、临床诊断、治疗及管理,旨在提高大豆和花生过敏的精准诊断和个性化治疗水平。.