Blended phytogenics as an alternative to growth-promoting antibiotics in newly weaned piglets

Trop Anim Health Prod. 2024 Dec 23;57(1):5. doi: 10.1007/s11250-024-04225-2.

Abstract

The research aimed to evaluate the effects of a commercial blend of phytogenic compounds on the digestibility, antioxidant system, intestinal microbiota, and performance of weaned piglets. Two experiments compared three treatments (diets): control, zinc bacitracin (300 g/t) and blended phytogenic compounds (400 g/t). The first experiment analised of digestibility of the dry matter, organic matter, crude protein, crude energy and metabolizable energy, in addition to blood parameters and gut microbiota in 15 piglets commercial cross-bred, weaned at 28 days of age, castrated males, weighing 9.40 ± 0.622 kg housed in metabolic cages. In the second experiment, performance was evaluated on 108 piglets commercial cross-bred, weaned at 26 days of age, females and castrated males, weighing 7.52 ± 0.356 kg housed in collective stalls with 1,5 m² (3 animals/stall). A completely randomized design was used. The data were subjected to analysis of variance, and the means compared by the Tukey test at 5% significance. There were no differences in piglet digestibility and performance. There was a reduction in the levels of the enzyme superoxide dismutase, lipid peroxidation, and haptoglobulin, and an increase in the levels of the non-protein thiol compound and IgA for the animals receiving the phytogenic compound when compared with the piglets of the other treatments (p < 0.05). A tendency in diversity was observed in the intestinal microbiota of piglets receiving the phytogenic compound in the feed (p = 0.054). Due to its important role in the antioxidant system and intestinal microbiota, it is suggested that the blend of phytogenic additives can replace antibiotics growth promoters in the diet of newly weaned piglets.

Keywords: Essencial oils; Growth promoter; Swine; Weaning.

MeSH terms

  • Animal Feed* / analysis
  • Animal Nutritional Physiological Phenomena / drug effects
  • Animals
  • Anti-Bacterial Agents* / administration & dosage
  • Anti-Bacterial Agents* / pharmacology
  • Antioxidants
  • Bacitracin / administration & dosage
  • Bacitracin / pharmacology
  • Diet* / veterinary
  • Dietary Supplements / analysis
  • Digestion / drug effects
  • Female
  • Gastrointestinal Microbiome* / drug effects
  • Male
  • Random Allocation
  • Sus scrofa / growth & development
  • Swine
  • Weaning*

Substances

  • Anti-Bacterial Agents
  • Antioxidants
  • Bacitracin