Identification and Characterization of Vancomycin-Resistant Staphylococcus aureus CC45/USA600, North Carolina, USA, 2021

Emerg Infect Dis. 2025 Jan;31(1):194-196. doi: 10.3201/eid3101.241573.

Abstract

Vancomycin-resistant Staphylococcus aureus (VRSA) is a rare but serious public health concern. We describe a VRSA case in North Carolina, USA. The isolate from the case belonged to the USA600 lineage and clonal complex 45. No transmission was identified. Confirmed VRSA cases should include a thorough investigation and public health response.

Keywords: CC45/USA600; North Carolina; United States; VRSA; VanA; antimicrobial resistance; bacteria; public health; resistant Staphylococcus aureus; staphylococci; vancomycin.

Publication types

  • Case Reports

MeSH terms

  • Anti-Bacterial Agents* / pharmacology
  • Anti-Bacterial Agents* / therapeutic use
  • Humans
  • Male
  • Microbial Sensitivity Tests
  • North Carolina / epidemiology
  • Staphylococcal Infections* / drug therapy
  • Staphylococcal Infections* / epidemiology
  • Staphylococcal Infections* / microbiology
  • Staphylococcus aureus / drug effects
  • Staphylococcus aureus / genetics
  • Staphylococcus aureus / isolation & purification
  • Vancomycin / pharmacology
  • Vancomycin / therapeutic use
  • Vancomycin Resistance / genetics

Substances

  • Anti-Bacterial Agents
  • Vancomycin