CD30- and CD56-positive atypical intravascular lymphocytes of the uterine cervix, mimicking intravascular lymphoma: A case report and review of the literature

J Clin Exp Hematop. 2024;64(4):328-331. doi: 10.3960/jslrt.24058.

Abstract

Intravascular accumulation of atypical large lymphoid cells is a rare condition that necessitates a differential diagnosis of intravascular lymphoma (IVL). Recently, a non-neoplastic condition known as benign atypical intravascular CD30+ T-cell proliferation (BAITP) has been identified. This condition is characterized by CD30+ and CD3+ or CD4+ atypical T-cells and is often associated with trauma and chronic inflammation. This case highlights atypical intravascular lymphoid cells of the uterine cervix that are positive for CD30 and CD56 and can mimic IVL.

Keywords: CD30; CD56; atypical T cells; cervix; intravascular lymphoma.

Publication types

  • Case Reports
  • Review

MeSH terms

  • CD56 Antigen* / metabolism
  • Cervix Uteri / pathology
  • Diagnosis, Differential
  • Female
  • Humans
  • Ki-1 Antigen* / metabolism
  • Lymphoma / diagnosis
  • Lymphoma / pathology
  • Vascular Neoplasms / diagnosis
  • Vascular Neoplasms / pathology

Substances

  • Ki-1 Antigen
  • CD56 Antigen
  • NCAM1 protein, human